Anti-inflammatory Effect of n-Hexane Fraction of Kentut leaves (Paederia scandens L.) on Male White Rats (Rattus novergicus)

Muhammad Ilfan  Yazid; Laode Rijai; Islamudin Ahmad

doi:10.70392/mpbb3e50

Authors

Muhammad Ilfan Yazid Fakultas Farmasi, Universitas Mulawarman Author
Laode Rijai Fakultas Farmasi, Universitas Mulawarman Author
Islamudin Ahmad Fakultas Farmasi Universitas Mulawarman Author https://orcid.org/0000-0002-7429-9215

DOI:

https://doi.org/10.70392/mpbb3e50

Keywords:

Antiinflammation, effective dose, in vivo, Paederia scandens

Abstract

The anti-inflammatory effect of fart plant leaf extract (Paederia scandens L.) on white rats (Rattus norvegicus) has been carried out. This research shows that the effective dose of the n-hexane fraction of P. scandens leaf extract provides the best anti-inflammatory effect on white rats' feet soles. The study used an artificial edema formation method and periodically measured the volume of white mice's legs using a plethysmometer. The doses used for the extract are 100mg/200g BW, 150mg/200g BW, and 200mg/200g BW. The research data was observed visually. The effective dose of P. scandens leaf extract, which has the best anti-inflammatory effect, is 150mg/200g BW.

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