Pharmacognosic Study and Determination of Marker Compounds Soursop Leaves (Annona muricata)


  • M. Arifuddin Mulawarman University Author
  • Muhammad Faisal Fakultas Kesehatan Masyarakat, Universitas Mulawarman Author
  • Erwin Samsul Fakultas Farmasi, Universitas Mulawarman Author
  • Baso Didik Hikmawan Fakultas Farmasi, Universitas Mulawarman Author
  • Wisnu Prabowo Fakultas Farmasi, Universitas Mulawarman Author
  • Islamudin Ahmad Fakultas Farmasi, Universitas Mulawarman Author
  • Arsyik Ibrahim Fakultas Farmasi, Universitas Mulawarman Author



Soursop leaves, Annona muricata, pharmacognosy, markers


Soursop (Annona muricata) is reported to have great efficacy in traditional medicine in Indonesia so it is very vulnerable to being faked or sold as low quality. Apart from having a delicious fruit taste, Soursop leaves have also been used as an effective cancer medicine by the public and have been scientifically proven so that Soursop can be used as a phytopharmaceutical product.

Therefore, it is necessary to carry out research to determine pharmacognosy parameters and marker compounds as ingredients needed to obtain the authenticity of simplicia and plant extracts. This research includes macroscopic and microscopic examination of leaves, macroscopic and microscopic examination of simplicia, fluorescence characteristics of simplicia, determining the solubility of methanol extract in various non-polar and polar solvents as well as the characteristics of marker compounds that can be used as alternatives to existing marker compounds from Soursop (Annona muricata). The research results obtained are important information as a stage for the identification and standardization of soursop leaves (Annona muricata) as a raw material for herbal medicine.


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Data Availability Statement

All data included in whole paper.

How to Cite

M. Arifuddin, Faisal, M., Samsul, E., Hikmawan, B. D., Prabowo, W., Ahmad, I., & Ibrahim, A. (2024). Pharmacognosic Study and Determination of Marker Compounds Soursop Leaves (Annona muricata). Journal of Pharmaceuticals and Natural Sciences, 1(1), 41-46.