Tyrosinase Inhibitory Activity of The Extracts from Garcinia lateriflora Blume var. Javanica Boerl, Garcinia fruticosa Lauterb, and Garcinia xanthochymus

Neneng Siti Silfi Ambarwati; Berna Elya

doi:10.70392/drty6950

Authors

Neneng Siti Silfi Ambarwati Universitas Negeri Jakarta Author https://orcid.org/0000-0002-3025-631X
Berna Elya Universitas Indonesia Author

DOI:

https://doi.org/10.70392/drty6950

Keywords:

Tyrosinase inhibitory, Garcinia lateriflora Blume var. javanica Boerl, Garcinia fruticose Lauterb, Garcinia xanthocymus

Abstract

Tyrosinase overexpression in humans increases melanin production in the skin, which may have hyperpigmentation-causing effects. In this study, various extracts from the Garcinia lateriflora Blume var. Javanica Boerl, Garcinia fruticosa Lauterb, and Garcinia xanthochymus plants were tested for their ability to inhibit the tyrosinase enzyme. The results showed that the G. fruticosa Lauterb stem bark hexane extract had the highest activity followed succesively by the G. lateriflora Blume var javanica Boerl leaf methanol extract, G xanthochymus mesocarp hexane extract, G. xanthochymus mesocarp methanol extract. The results show that the G. fruticosa Lauterb stem bark hexane extract has the highest tyrosinase inhibitory activity (45.61 ± 1.58%) among the four extracts and the tyrosinase inhibitory activity of kojic acid (65.07 0.86%).

Author Biographies

Neneng Siti Silfi Ambarwati, Universitas Negeri Jakarta

Cosmetology Department
Berna Elya, Universitas Indonesia

Phytochemistry

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